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- A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT. Dec 2009.

- A Gain-of-Function Mutation of JAK2 in Myeloproliferative Disorders, 2005.

- A Large Proportion of Patients With a Diagnosis of Essential Thrombocythemia Do Not Have a Clonal Disorder and May Be at Lower Risk of Thrombotic Complications. 1999.

- A latent form of essential thrombocythemia presenting as portal cavernoma. Nov 2009.

- A longitudinal study of the JAK2(V617F) mutation in myelofibrosis with myeloid metaplasia: analysis at two time points. 2006.

- A Multidisciplinary Investigation of a Polycythemia Vera Cancer Cluster of Unknown Origin. 2010.

- A new JAK2 gene mutation in patients with polycythemia vera and splanchnic vein thrombosis. 2007.

- A Simple, Rapid, and Sensitive Method for the Detection of the JAK2 V617F Mutation. 2007.

- A Study of Histamine in Myeloproliferative Disease. 1965

- A Unique Activating Mutation in JAK2 (V617F) is at the Origin of Polycythemia Vera and Allows a New Classification of Myeloproliferative Diseases. Full text

- A White Hand and a Red Hand —Erythromelalgia. Full text with photos. Oct 2010.

- Aberrant expression of microRNA in polycythemia vera

- Abnormalities affecting tyrosine kinase signalling in atypical myeloproliferative disorders. University thesis. 2009

- About Primary Myelofibrosis (PMF): A video of Dr Ruben Mesa of the Mayo Clinic.

- Absence of SKP2 expression attenuates BCR-ABL?induced myeloproliferative disease. 2008.

- Absence of the JAK2 V617F mutation in patients with arterial thrombosis without overt myeloproliferative disease. 2008.

- Absence of the V617F JAK2 Mutation in the Lymphoid Compartment in a Patient with Essential Thrombo- cythemia and B-Chronic Lymphocytic Leukemia and in Two Relatives with Lymphoproliferative Disorders.

- Acquired Melanonychia due to treatment of ET with hydroxyurea. Sep 17th 2009.

- Acquisition of the V617F mutation of JAK2 is a late genetic event in a subset of patients with myeloproliferative disorders. 2006.

- Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.

- Activation of JAK2-V617F by components of heterodimeric cytokine receptors. April 2010.

- Acute leukemia in polycythemia vera: an analysis of 1638 patients enrolled in a prospective observational study

- Acute variceal bleeding in a patient with idiopathic myelofibrosis successfully treated with endoscopic variceal band ligation and chemotherapy: a case report. Full text, 2010.

- Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders. 2007.

- Advances in the Therapy of Chronic Idiopathic Myelofibrosis. 2006.

- Advances in the treatment of hematological malignancies: current treatment approaches in multiple myeloma. Annals of Oncology, 2007.

- Advances in Understanding and Management of Myeloproliferative Neoplasms. April 2009

- Adverse effects and benefits of two years of anagrelide treatment for thrombocythemia in chronic myeloproliferative disorders. 2005.

- Agnogenic Myeloid Metaplasia With Myelofibrosis

- Allogeneic Blood and Marrow Transplant Guidebook: Stanford Hospital. (January 2005)

- Allogeneic hematopoietic stem cell transplantation in myelofibrosis: the 20-year experience of the Gruppo Italiano Trapianto di Midollo Osseo. 2008

- Allografting Older Patients?Myths and Realities

- American Academy of Pain Management

- An Inconvenient Truth. Jerry Spivak, Apr 2010.

- An MPD case history, slide show.

- An Open Letter to those without Invisible Disability or Chronic Illness

- Anagrelide drug information. AHFS Consumer Medication Information.

- Anagrelide drug sheet

- Anagrelide-associated cardiomyopathy in polycythemia vera and essential thrombocythemia. 2004.

- Analyzing the Complex Relationship between Diet & Cancer (AACR Frontiers in Cancer Prevention Research Conference)

- Another Lnk to STAT activation. Full text, August 2010.

- Antidepressants: Another weapon against chronic pain

- Antiplatelet drugs for polycythaemia vera and essential thrombocythemia. Full text, 2008.

- Assessing karyotype precision by microarray-based comparative genomic hybridization in the myelodysplastic/myeloproliferative syndromes. Full text, Nov 2010

- Assessing New Therapies and Their Overall Impact in Myelofibrosis. Full text, 2010.

- Asymmetric dimethylarginine levels in essential thrombocythemia - a retrospective analysis. Full text, Dec 2010.

- Atypical Myeloproliferative Disorders: Diagnosis and Management. 2006.

- Autoimmunity and the risk of myeloproliferative neoplasms. Full text article, Jan 2010.

- Bcr/abl-Negative, Classic Myeloproliferative Disorders: Diagnosis and Treatment. 2005.

- Biology and Treatment of Primary Myelofibrosis. 2007.

- Blood cell activation in myeloproliferative neoplasms. Full text, 2009.

- BMT infonet

- Bone and bone marrow: The same organ. Oct 2010.

- Bone Marrow Aspiration and Biopsy : Labtests Online.

- Bone marrow biopsy and aspiration. Mayo Clinic, updated Nov 2009.

- Bone Marrow Disorders: Labtests online

- Bone Marrow Fibrosis and Diagnosis of ET. Oct 2009.

- Bone marrow pathology in ET: interobserver reliability and utility for identifying disease subtypes

- Bone marrow trephine biopsy. Full text.

- Bone Marrow, Thymus and Blood: Changes across the lifespan. Full text, Jan 2010.

- British Bone Marrow Registry.

- Busulfan drug sheet

- Can Electronic Clinical Documentation Help Prevent Diagnostic Errors? March 2010.

- Case of Bilateral Retinal Neovascularization Associated with Chronic Idiopathic Myelofibrosis. April 2010.

- CBMTG Guidance on Stem Cell Transplantation for Myeloproliferative Disorders. Full text. 2009.

- Changes that make a gene faulty

- Changes to the Genetic Code

- Changing the Culture of Clinical Trials: Reviving a Failing Effort. Full text, Sep 2010.

- Characteristics and clinical correlates of MPL 515W>L/K mutation in essential thrombocythemia. 2008.

- Characterization of 35 new cases with four different MPLW515 mutations and essential thrombocytosis or primary myelofibrosis

- Chemotherapy-Related Fatigue Is Helped by Varying Intensities and Types of Exercise

- Childhood idiopathic myelofibrosis: a case report and review of literature.

- Childhood polycythemia vera and essential thrombocythemia: does their pathogenesis overlap with that of adult patients? 2008.

- Choosing between stem cell therapy and drugs in myelofibrosis. Full text. 2008.

- Chromosomol translocations in chronic myeloproliferative diseases

- Chronic Myeloproliferative Neoplasm 2008 Who Classification Proposal. From Morphology to Biology. A 31 page slide show.

- Chronic care in America: A 21st century Challenge.

- Chronic Fatigue in Primary Care

- Chronic idiopathic myelofibrosis: Macmillan Cancer Support.

- Chronic Illness Lecture: Psychological Aspects of MPDs. Given at St Thomas's Hospital 2004.

- Chronic Myelogenous Leukemia: EMedicine.

- Chronic myeloid leukaemia (CML): Cancer Research UK.

- Chronic myeloid leukaemia: Macmillan Cancer Support.

- Chronic myeloid leukemia 2010: where are we now and where can we go? Full text, Jan 2011.

- Chronic Myeloproliferative Disorders Treatment

- Chronic Myeloproliferative Disorders: Cleveland Clinic

- Chronic pain treatments work better together, for neuropathic pain. News, Oct 2009

- Class prediction models of thrombocytosis using genetic biomarkers. Fulltext, Jan 2010.

- Classification, Diagnosis and Management of Myeloproliferative Disorders in the JAK2V617F Era. 2006.

- Clinical profile of homozygous JAK2 617V>F mutation in patients with polycythemia vera or essential thrombocythemia. 2007.

- Clinical relevance of JAK2 (V617F) mutant allele burden

- Clinical trials for MPDs

- Clinical trials with anti-angiogenic agents in hematological malignancies. Full text, June 2010.

- Clonal heterogeneity in polycythemia vera patients with JAK2 exon12 and JAK2-V617F mutations. 2008.

- CML—The Changing Landscape of Front-line Therapy: Part I: Interview With Dr. Jane Apperley. Nov 2010.

- CML—What to do About Imatinib Resistance; When to Consider Transplant: Part II: Interview With Dr. Jane Apperley. Nov 2010.

- Comfort I and Comfort II clinical trials web site.

- Comorbidities and Hematopoietic Cell Transplantation Outcomes. Full text, 2010.

- Comparison of different criteria for the diagnosis of primary myelofibrosis reveals limited clinical utility for measurement of serum lactate dehydrogenase. June 2010.

- Concordance of assays designed for the quantification of JAK2V617F: a multicenter study. Nov 2008.

- Controversies in Multi-institutional Phase I Clinical Trials. Aug 2009. Full text.

- Coping Strategies in the Presence of One's Own Impending Death from Cancer

- Cord Blood Transplants. August 2009. Full text.

- Correlation between leukocytosis and thrombosis in Philadelphia- negative chronic myeloproliferative neoplasms

- Dasatinib Approved for Early Chronic Myeloid Leukemia. Full text, Oct 2010.

- Dasatinib versus Imatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia. Full text, June 2010.

- Deactylase inhibition in myeloproliferative neoplasms. Dec 2010.

- Deciding on Transplantation for Myelofibrosis: Setting the Record Straight. 2004.

- Decreased serum prohepcidin concentration in patients with polycythemia vera. Nov 2009.

- Deep sequencing reveals double mutations in cis of MPL exon 10 in myeloproliferative neoplasms. Abstract, Jan 2011.

- Depression in older cancer patients can be effectively treated with collaborative approach

- Depression in older cancer patients more effectively treated

- Dermatomyositis-like eruption induced by hydroxyurea: a case report. Full text, 2009.

- Detection of JAK2 exon 12 mutations in 15 patients with JAK2V617F negative polycythemia vera. 2009.

- Determinants of platelet number and regulation of thrombopoiesis. Full text, 2009.

- Diagnosis from the Blood Smear

- Diagnosis of myeloproliferative neoplasms: Dr Claire Harrison. Full text, June 2010.

- Diagnostic and therapeutic management of eosinophilia-associated chronic myeloproliferative disorders. 2007.

- Diagnostic Assays for the JAK2 V617F Mutation in Chronic Myeloproliferative Disorders. 2006.

- Discontinuation of Imatinib in Patients With Chronic Myeloid Leukaemia Who Have Maintained Complete Molecular Remission for at Least 2 Years: The Prospective, Multicentre Stop Imatinib (STIM) Trial. Full text, Nov 2010.

- Disease anticipation in familial myeloproliferative neoplasms. 2008.

- Diseases Treated with Umbilical Cord Blood.

- Distinct Clinical Phenotypes Associated with JAK2V617F Reflect Differential STAT1 Signaling. Full text, Nov 2010.

- Does JAK2 1849G>T initiate polycythemia vera? 2006.

- Does primary myelofibrosis involve a defective stem cell niche? From concept to evidence. 2008.

- Dr Ruben Mesa video

- Dr Ruben Mesa video: Chronic Myeloid Leukemia-Mayo Clinic. May 2010.

- Dr Ruben Mesa video: Myelofibrosis Update -Mayo Clinic. May 2010.

- Dr Ruben Mesa: PV video, March 2010.

- Durable responses to imatinib in patients with PDGFRB fusion gene?positive and BCR-ABL?negative chronic myeloproliferative disorders. 2007.

- Durable Responses to Thalidomide-Based Drug Therapy for Myelofibrosis With Myeloid Metaplasia. 2004.

- Effect of JAK2 V617F on thrombotic risk in patients with essential thrombocythemia: measuring the uncertain. Full. 2008.

- Efficacy and safety of long-term use of hydroxyurea in young patients with essential thrombocythemia and a high risk of thrombosis.2003

- Efficacy and Safety of Low-Dose Aspirin in Polycythemia Vera

- Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-Induced Polycythemia Vera

- Ehow: Myelofibrosis

- Elevated procoagulant microparticles expressing endothelial and platelet markers in essential thrombocythemia

- EMedicineHealth: Polycythemia

- Eosinophilic Heart Disease in Acute Myeloproliferative Disorder. 2007.

- Epigenetic Modifications: New Therapeutic Targets in Primary Myelofibrosis. Full text, June 2010.

- Erythromelalgia, photo and article, Jan 2010

- Erythromelalgia: Vasculopathy, Neuropathy, or Both? Full text, 2003.

- Erythropoietin and cancer, a double-edged sword

- Erythropoietin. MacMillan Cancer Support site.

- Essential thrombocythaemia (ET): Macmillan Cancer Support.

- Essential Thrombocythemia Beyond the First Decade: Life Expectancy, Long-term Complication Rates, and Prognostic Factors. 2006. Full text.

- Essential thrombocythemia, thrombosis and enhanced platelet regeneration: Is once daily dose of aspirin enough? 2010.

- Essential Thrombocythemia-Mayo Clinic: Ruben Mesa video.

- Essential thrombocythemia. Free Access article.

- Etiology, Management, and Outcome of the Budd-Chiari Syndrome. Full text, Aug 2009.

- ETV6-ABL1-positive "chronic myeloid leukemia": clinical and molecular response to tyrosine kinase inhibition. Full text, Feb 2011.

- Evidence Based Depression care

- Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis. 2007.

- Extent of hematopoietic involvement by TET2 mutations in JAK2V617F polycythemia vera. Full text, Jan 2011.

- Extramedullary hemopoiesis with undiagnosed, early myelofibrosis causing spastic compressive myelopathy: Case report and review. Full text, Feb 2010.

- Familial Chronic Myeloproliferative Disorders: Clinical Phenotype and Evidence of Disease Anticipation. Full text, 2007.

- Familial polycythemia due to truncations of the erythropoietin receptor.

- Fat Tissue May Be a Source of Valuable Blood Stem Cells, Study Says. News, Feb 1st, 2010.

- Focus on myeloproliferative diseases and myelodysplastic syndromes

- Frequency of heterozygous TET2 deletions in myeloproliferative neoplasms. Full text, Sep 2010.

- Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms. Full text, 2009.

- Frequent reduction or absence of detection of the JAK2-mutated clone in JAK2 V617F-positive patients within the first years of hydroxyurea therapy. 2008.

- From 1 to 2 mutated JAK2: the road from ET to PV. 2006.

- From Palliation to Epigenetic Therapy in Myelofibrosis. 2008.

- Future Therapies for the Myeloproliferative Neoplasms. Full text, Nov 2010.

- GP Notebook

- Guideline for investigation and management of adults and children presenting with a thrombocytosis. Full text, June 2010.

- Guidelines for the diagnosis and treatment of patients with polycythemia vera, essential thrombocythemia and primary myelofibrosis. Nordic MPD Group. March 2008.

- Help with medical expenses etc

- Hematologic Malignancies Program. Mayo Clinic.

- Hematopoietic Cell Transplantation for Adult Patients With Myelodysplastic Syndromes and Myeloproliferative Disorders. Mayo Clinic.

- Hereditary thrombocytosis caused by MPLSer505Asn is associated with a high thrombotic risk, splenomegaly and progression to bone marrow fibrosis. Full text, 2009.

- High Frequency of Endothelial Colony Forming Cells Marks a Non-Active Myeloproliferative Neoplasm with High Risk of Splanchnic Vein Thrombosis. Full text, Dec 2010.

- High molecular response rate of polycythemia vera patients treated with pegylated interferon ?2a. Full text.

- High prevalence of restless legs syndrome among patients with polycytemia vera treated with venesection. Full text, June 2010.

- High-resolution single-nucleotide polymorphism array-profiling in myeloproliferative neoplasms identifies novel genomic aberrations. Full text, August 2010.

- Histone deacetylase: a potential therapeutic target for fibrotic disorders. Full text, Nov 2010.

- Histopathology Bone Marrow--Chronic idiopathic myelofibrosis video.

- Hitting the Target in Myeloproliferative Neoplasms, ASH conference 2010.

- Host genetic variation contributes to phenotypic diversity in myeloproliferative disorders. 2008.

- How do JAK2-inhibitors work in myelofibrosis: An alternative hypothesis. Full text, Sep 2009.

- How I treat essential thrombocythemia. Full text, Feb 2011.

- How I treat influenza in patients with hematologic malignancies. Full text, Feb 2010.

- How I treat patients with polycythemia vera. 2007.

- How I treat symptomatic splenomegaly in patients with myelofibrosis, 2009.

- How I treat symptomatic splenomegaly in patients with myelofibrosis: Ruben A. Mesa, Mayo Clinic. May 2009

- How, When, & If to Tell Clinical Trial Participants the Results: Oncology Times, Mar 2010.

- HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans. Full text, Sep 2010.

- Hydroxycarbamide (Hydrea, HU) drug sheet

- Hydroxyurea Compared with Anagrelide in High-Risk Essential Thrombocythemia

- Hydroxyurea does not appreciably reduce JAK2 V617F allele burden in patients with polycythemia vera or essential thrombocythemia. April 2010.

- Hydroxyurea dose impacts hematologic parameters in polycythemia vera and essential thrombocythemia but does not appreciably affect JAK2-V617F allele burden. March 2011.

- Hydroxyurea drug information. AHFS Consumer Medication Information.

- Hydroxyurea in essential thrombocytemia: rate and clinical relevance of responses by European LeukemiaNet criteria. Full text, May 2010.

- Hydroxyurea induced oscillations in twelve patients with polycythemia vera. March 2010.

- Hypercalcemia complicating leukemic transformation of agnogenic myeloid metaplasia-myelofibrosis. 1999.

- Hyperkalaemia associated with hydroxyurea in a patient with polycythaemia vera, Dec 2010.

- Hypothesis: How do JAK2-inhibitors work in myelofibrosis. Full text, April 2009.

- Identification during the follow-up of time-dependent prognostic factors for the competing risks of death and blast phase in primary myelofibrosis: a study of 172 patients. Full text, March 2010.

- Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele. August 2009.

- IDH1 and IDH2 mutations in myeloid neoplasms – Novel paradigms and clinical implications. Full text, Oct 2010.

- IDH1 and IDH2 mutations in myeloid neoplasms--novel paradigms and clinical implications. March 2011.

- IDH1 R132H mutation is a rare event in MPN as determined by a mutation specific antibody. Full text, June 2010.

- If I Had Polycythemia Rubra Vera: Video with Dr Josef Prchal. Dec 2008.

- Increased risk of lymphoid neoplasm in patients with myeloproliferative neoplasm: a study of 1,915 patients. Full text, Nov 2010.

- Increased risk of pregnancy complications in patients with essential thrombocythemia carrying the JAK2 (617V>F) mutation

- Increased risks of polycythemia vera, essential thrombocythemia, and myelofibrosis among 24 577 first-degree relatives of 11 039 patients with myeloproliferative neoplasms in Sweden. Sep 2008.

- Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and Pentraxin 3. Full text, Dec 2010.

- Influence of the JAK2 V617F mutation and inherited thrombophilia on the thrombotic risk among patients with essential thrombocythemia. March 2009

- Inhibition of the Bcl-xL Deamidation Pathway in Myeloproliferative Disorders Dec 2008.

- Interferon drug sheet

- Interferon-a therapy in bcr-abl-negative myeloproliferative neoplasms. Full text, 2008.

- Involvement of various hematopoietic-cell lineages by the JAK2V617F mutation in polycythemia vera. 2006.

- Is JAK2 V617F mutation more than a diagnostic index?: A meta-analysis of clinical outcomes in essential thrombocythemia

- Isolated Erythrocythemia: A Distinct Entity or a Sub-type of Polycythemia Vera? 2008.

- JAK2 617V>F?positive polycythemia rubra vera maintained by approximately 18 stochastic stem-cell divisions per year, explaining age of onset by a single rate-limiting mutation. 2007.

- JAK2 Exon 12 Mutations in Polycythemia Vera and Idiopathic Erythrocytosis

- JAK2 Exon 14 Deletion in Patients with Chronic Myeloproliferative Neoplasms. Full text, August 2010.

- JAK2 germline genetic variation affects disease susceptibility in primary myelofibrosis regardless of V617F mutational status: nullizygosity for the JAK2 46/1 haplotype is associated with inferior survival. Abstract 2009.

- JAK2 impairs stem cell function? Full text, Sep 2010.

- JAK2 Inhibitors and Myeloproliferative Neoplasms. Dec 2008. Full text.

- JAK2 Inhibitors for the treatment of myeloproliferative neoplasms. Tefferi. March 2010.

- JAK2 Inhibitors: Not the next Imatinib but researchers see other possibilities. 2009.

- JAK2 Mutations and Coronary Ischemia. Full text, July 2010.

- JAK2 Negative Polycythemia Vera. March 2011.

- JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders

- JAK2 Test: Labtests Online

- JAK2 V617F and MPL W515L/K mutations in Korean patients with essential thrombocythemia. Full text, Feb 2011.

- JAK2 V617F Constitutive Activation Requires JH2 Residue F595: A Pseudokinase Domain Target for Specific Inhibitors. Full text, June 2010.

- JAK2 V617F mutation in myelodysplastic syndrome, myelodysplastic syndrome/myeloproliferative neoplasm, unclassifiable, refractory anemia with ring sideroblasts with thrombocytosis, and acute myeloid leukemia. Mch 2010.

- JAK2 V617F Mutation in Patients With Catastrophic Intra-abdominal Thromboses. 2007.

- JAK2 V617F mutational status predicts progression to large splenomegaly and leukemic transformation in primary myelofibrosis

- JAK2-positive Philadelphia-negative myeloproliferative neoplasms. Full text, March 2011.

- JAK2: how many faces in MPDs? 2008.

- JAK2V617F mutation and spontaneous megakaryocytic or erythroid colony formation in patients with essential thrombocythaemia (ET) or polycythaemia vera (PV)

- JAK2V617F mutation for the early diagnosis of Ph? myeloproliferative neoplasms in patients with venous thromboembolism: a meta-analysis

- JAK2V617F Mutation Screening as Part of the Hypercoagulable Work-up in the Absence of Splanchnic Venous Thrombosis or Overt Myeloproliferative Neoplasm: Assessment of Value in a Series of 664 Consecutive Patients

- JAK2V617F mutational status and allele burden have little influence on clinical phenotype and prognosis in patients with post-polycythemia vera and post-essential thrombocythemia myelofibrosis

- JAK2V617F-negative ET Patients do not display constitutively active JAK/STAT signaling

- JAK2V617F: prevalence in a large Chinese hospital population

- JAKing up hematopoietic proliferation

- Janus Kinase 2: An Epigenetic ?Writer? that Activates Leukemogenic Genes. Full text, Jan 2010.

- Labtests Online UK

- Labtests Online US

- Lancet 2005: Definition of subtypes of ET and relation to PV based on JAK2 V617F mutation status: a prospective study

- Leg ulcers associated with hydroxyurea therapy. Full text, 2003.

- Lenalidomide therapy in myelofibrosis with myeloid metaplasia. 2006.

- Lessons Learned From the Development of Kinase Inhibitors. Sep 2009. Fulltext

- Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders. 2008.

- Leukemia and Lymphoma Research: The Myeloproliferative Disorders booklet. 32 pages.

- Leukemic transformation of polycythemia vera. Full text. 2005

- Leukocytosis (raised WBC) : Basics of Clinical Assessment

- Leukocytosis and Risk Stratification Assessment in Essential Thrombocythemia. 2008.

- Leukocytosis is a risk factor for recurrent arterial thrombosis in young patients with polycythemia vera and essential thrombocythemia. Full text, Feb 2010.

- Leukocytosis is a risk factor for thrombosis in essential thrombocythemia: interaction with treatment, standard risk factors, and Jak2 mutation status

- Limited effects on JAK2 mutational status after pegylated interferon alpha-2b therapy in polycythemia vera and essential thrombocythemia. 2006.

- LNK Mutations in JAK2 Mutation–Negative Erythrocytosis. Full text, Sep 2010.

- Local Trials site: Chronic MPDs.

- Long-term follow-up of essential thrombocythemia in young adults: treatment strategies, major thrombotic complications and pregnancies outcome - a Study of 76 patients

- Long-term Outcome of 231 Patients With Essential Thrombocythemia. Full text, 2005.

- Long-term recovery after hematopoietic cell transplantation: predictors of quality-of-life concerns. March 2010.

- Low-Dose Thalidomide Ameliorates Cytopenias and Splenomegaly in Myelofibrosis With Myeloid Metaplasia: A Phase II Trial.2004.

- Management of extreme thrombocytosis in otherwise low-risk essential thrombocythemia; does number matter? 2006.

- Management of Polycythemia Vera and Essential Thrombocythemia. 2005.

- Managing Chronic Fatigue Syndrome with The Pacing Approach

- Markers of Myeloproliferative Diseases in Childhood Polycythemia Vera and Essential Thrombocythemia

- Marrow Fibrosis Does Not Account for Circulating CD34+ Cells in Myelofibrosis with Myeloid Metaplasia. 2007.

- Marrow fibrosis in primary myelofibrosis. Atlas Image bank, 2009

- Mast cell burden and reticulin fibrosis in the myeloproliferative neoplasms: a computer-assisted image analysis study.

- Mature Survival Data for 176 Patients Younger Than 60 Years With Primary Myelofibrosis Diagnosed Between 1976 and 2005: Evidence for Survival Gains in Recent Years. Full Open Access text. Dec 2009.

- MD Anderson Cancer Center: Cancer-related Fatigue video

- Measurement of spleen volume by ultrasound scanning in patients with thrombocytosis: a prospective study

- Mechanisms of constitutive activation of Janus kinase 2-V617F revealed at the atomic level through molecular dynamics simulations. Full text, July 2010.

- Medicine.net: Muscle cramps

- Metabolism, Excretion and Pharmacokinetics of 14C-INCB018424, a Selective JAK1/2 Inhibitor, in Humans. Full text, August 2010.

- Methuselah conundrum: MPDs in the elderly. 2007.

- Methylation of the suppressor of cytokine signaling 3 gene (SOCS3) in myeloproliferative disorders

- Micromegakaryocytes in peripheral blood in idiopathic myelofibrosis. 2007.

- Mini-dose of thalidomide for treatment of primary myelofibrosis. Report of a case with complete reversal of bone marrow fibrosis and splenomegaly. 2007.

- Minimal Activity of the JAK2 Inhibitor CEP 701 in Myelofibrosis. Full text, April 2010.

- Minimal molecular response in polycythemia vera patients treated with imatinib or interferon alpha. Full text, 2006.

- Molecular & Cellular Basis of Myeloproliferative Disorders. Full text, Sep 2010.

- Molecular and clinical features of refractory anemia with ringed sideroblasts associated with marked thrombocytosis

- Molecular basis of myelodysplastic/myeloproliferative neoplasms. Full text, 2009.

- Molecular basis of myeloproliferative neoplasms. Slide show. 2010.

- Molecular basis of the diagnosis and treatment of polycythemia vera and essential thrombocythemia. 2006.

- Molecular mechanisms associated with leukaemic transformation of MPL-mutant myeloproliferative neoplasms. Full text, Sep 2010.

- Molecular pathophysiology of Philadelphia-negative myeloproliferative disorders : beyond JAK2 and MPL mutations

- Morphological evaluation of monocytes and monocyte precursors in bone marrow trephine biopsies - need for establishing diagnostic criteria

- MPDs: it's all in the family. 2008.

- MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort. 2008.

- MPLSer505Asn induced hereditary thrombocytosis is associated with a high thrombotic risk, splenomegaly and progression to bone marrow fibrosis

- MTHFR gene mutation in myeloproliferative neoplasms – is there any contribution to the thrombogenic risk. Oct 2010.

- Mutation in TET2 in Myeloid Cancers

- Mutation of JAK2 in the myeloproliferative disorders: timing, clonality studies, cytogenetic associations, and role in leukemic transformation. Full text. 2006.

- Myelodysplasia and Myeloproliferative Disorders in Children. 2004.

- Myelodysplastic syndromes with bone marrow fibrosis. Full text, Feb 2011.

- Myelofibrosis and Megakaryocyte Clustering. 2006.

- Myelofibrosis with myeloid metaplasia following essential thrombocythaemia: actuarial probability, presenting characteristics and evolution in a series of 195 patients. Full text, 2002.

- Myelofibrosis with myeloid metaplasia: targeted therapy. 2007.

- Myelofibrosis-Associated Lymphoproliferative Disease: Retrospective Study of 16 Cases and Literature Review, Full text, Oct 2009.

- Myelofibrosis: Thalidomide Finds a New Disease. 2004.

- Myelofibrotic transformation in essential thrombocythemia

- Myeloid Neoplasms slides by Dr Tefferi.

- Myeloproliferative Disease in Pregnancy and Other Management Issues. 2006.

- Myeloproliferative disease in the pathogenesis and survival of Budd-Chiari syndrome. 2006.

- Myeloproliferative Disorder?associated Massive Splenomegaly. Full text, April 2008

- Myeloproliferative disorders: David P. Steensma and Robert E. Richard. 56 page book chapter.

- Myeloproliferative disorders: Ross L. Levine and D. Gary Gilliland

- Myeloproliferative neoplasms, Atlas Image set. Full text, Nov 2009.

- Myeloproliferative Neoplasms: Genetic Trailblazers. March 2010.

- Myeloproliferative Neoplasms: Laboratory Support of Diagnosis and Management.

- Myeloproliferative Neoplasms: WHO 2008 classification. Slide view with photos.

- National Cancer Institute: Fatigue, Health Professional Version

- National Cancer Institute: Fatigue, Patient Version

- Natural History of Erythromelalgia: Presentation and Outcome in 168 patients

- Navigating the Evolving Paradigms in the Diagnosis and Treatment of Myeloproliferative Disorders: Ruben A Mesa. 2007.

- Neoplastic blood cells become pluripotent. Full text, 2009.

- Neoplastic Disorders of the Spleen. 37 page slide show. 2007.

- New Advances in the Pathogenesis and Therapy of Essential Thrombocythemia. 2008.

- New hope in the horizon: cancer stems cells. March 2010.

- New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment

- No association between myeloproliferative neoplasms and the Crohn?s disease-associated STAT3 predisposition SNP rs744166. Full text, Feb 2010.

- Novel Agents for Intractable Itch

- Novel CML Drug Active After Failures of Imatinib, Dasatinib, and Nilotinib. OncologyStat, Jan 2011.

- Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms. Full text, August 2010.

- Novel therapies for Myeloproliferative Neoplasms. Oct 2010.

- Obesity and the Risk for a Hematological Malignancy: Leukemia, Lymphoma, or Myeloma. Full text, Oct 2010. (includes MPDs)

- Observation versus antiplatelet therapy as primary prophylaxis for thrombosis in low-risk essential thrombocythemia. Full text, August 2010.

- On the Molecular Origins of the Chronic Myeloproliferative Disorders: It All Makes Sense

- Oncogenic JAK1 and JAK2-activating mutations resistant to ATP-competitive inhibitors.

- Oncogenic Signals as Treatment Targets in Classic Myeloproliferative Neoplasms

- Ongoing Study of First-Ever Drug Therapy for Myelofibrosis. Full text, Dec 2009.

- Oral Complications of Cancer Chemotherapy

- Outcome of 122 pregnancies in essential thrombocythemia patients: A report from the Italian registry.

- Outcomes After Allogeneic Hematopoietic-Cell Transplant Dramatically Better. Full text, Dec 2010.

- p53 Lesions in Leukemic Transformation. Full text, Feb 2011.

- Pain Awareness Site

- Pathogenesis and management of essential thrombocythemia. Full text, Philip Beer, Anthony Green, Cambridge 2009.

- Pathogenesis of Myelofibrosis With Myeloid Metaplasia. 2005.

- Pathology of Autoimmune Myelofibrosis. Full text, 2001.

- Pathophysiology of thrombosis in myeloproliferative neoplasms. Full text, 2011.

- Patients on Antiplatelet Therapy Should Anticipate Frequent Minor Hemorrhage. Full text, Dec 2010.

- Pediatric patients with essential thrombocythemia are mostly polyclonal and V617FJAK2 negative

- Peg IFN Study Summary

- Pegasys videos.

- Pegylated Interferon Alfa-2a Yields High Rates of Hematologic and Molecular Response in Patients With Advanced Essential Thrombocythemia and Polycythemia Vera

- Pegylated interferon for the treatment of high risk essential thrombocythemia: results of a phase II study. Full text, 2005.

- Peritonitis in myelofibrosis: a cautionary tale. Full text, Dec 2010.

- Perspectives in MPDs: Team Insights with the Patient in Mind. 2009.

- Perspectives on thrombosis in essential thrombocythemia and polycythemia vera: is leukocytosis a causative factor?

- Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis. Full text, Feb 2010.

- Phase I Trial Indicates Ponatinib May Thwart Most Resistant CML. News from ASH 2010.

- Philadelphia Chromosome?Negative Myeloproliferative Disorders: An Historical Perspective. 2008.

- Physical performance, depression, immune status and fatigue in patients with hematological malignancies after treatment. Annals of Oncolgy, 2004. Full text.

- Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells. June 2010.

- Pivotal contributions of megakaryocytes to the biology of idiopathic myelofibrosis. 2007.

- Platelets and Thrombosis in Myeloproliferative Diseases. Full text, 2005.

- Plenary session 4: Cell signaling targets: Development of JAK inhibitors for the treatment of human neoplasm. April 2010.

- Plenary session 9: Tyrosine kinase drug targets. Full text, April 2010.

- Polycythaemia vera (PV): Macmillan Cancer Support.

- Polycythemia Vera and Cerebrovascular Events: A powerpoint presentation. 2010.

- Polycythemia Vera and Essential Thrombocythemia in a General Population. 2003.

- Polycythemia Vera and JAK2 Testing Information: Pennsylvania Dept of Health (re the PV cluster in Schuylkill, Carbon and Luzerne counties). 2010.

- Polycythemia vera erythroblasts: too tough to die. 2006.

- Polycythemia Vera: The Natural History of 1213 Patients Followed for 20 Years. 1995.

- Population-Based Incidence and Survival Figures in Essential Thrombocythemia and Agnogenic Myeloid Metaplasia: An Olmsted County Study, 1976?1995. 1999. Full text.

- Postpolycythaemic myelofibrosis: frequency and risk factors for this complication in 116 patients.

- Postsurgery outcomes in patients with polycythemia vera and essential thrombocythemia: a retrospective survey

- Practice guidelines for the therapy of essential thrombocythemia. A statement from the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group. 2004.

- Practice patterns for evaluation, consent, and care of related donors and recipients at hematopoietic cell transplantation centers in the United States. June 2010.

- Preclinical drug profiles: AC013310, A potent JAK2/TYK2 inhibitor, provides protection in multiple myeloproliferative disease models. April 2010.

- Predictive Factors for Outcome And Response in Patients Treated With Second Generation Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia in Chronic Phase Post Imatinib Failure. Nov 2010.

- Prefibrotic myelofibrosis: is this diagnosis valid?

- Presenting results with confidence, Full text, 2009.

- Prevalence of JAK2 V617F mutation in Indian patients with chronic myeloproliferative disorders. Full text, Oct 2010.

- Prevention of thrombosis in polycythemia vera and essential thrombocythemia

- Primary autoimmune myelofibrosis in a 36-year-old patient presenting with isolated extreme anemia. Full text, Jan 2010.

- Problems in Bone Marrow Pathology. 2000.

- Profiling gene expression in thrombocytes: novel insights into essential thrombocythemia. E-Letter, April 15th 2010.

- Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia. 2006.

- Prognostic implications of the European consensus for grading of bone marrow fibrosis in chronic idiopathic myelofibrosis. 2008.

- Prognostic relevance of anemia and transfusion dependency in myelodysplastic syndromes and primary myelofibrosis. Full text, Jan 2011.

- Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: Recommendationsfrom an ad hoc international expert panel.

- Psychological flexibility in adults with chronic pain: A study of acceptance, mindfulness, and values-based action in primary care. Full text, Jan 2010.

- Public summary of opinion on orphan designation: Givinostat for the treatment of polycythaemia vera. 2010.

- Pulmonary Arterial Hypertension and Chronic Myeloproliferative Disorders. 2006.

- Pulmonary Hypertension Associated with Myeloproliferative Disorders: A Retrospective Study of Ten Cases. 2007.

- Quantitative Evaluation of Bone Marrow Angiogenesis in Idiopathic Myelofibrosis. 2006.

- Radionuclide (isotope) scan

- Rapid decline of JAK2V617F levels during hydroxyurea treatment in patients with polycythemia vera and essential thrombocythemia. 2008.

- Rapid identification of JAK2 exon 12 mutations using high resolution melting analysis. 2008.

- Rare thromboses of cerebral, splanchnic and upper-extremity veins. A narrative review. Full text, June 2010.

- Recent Advances in the Diagnosis and Treatment of Hypereosinophilic Syndromes

- Recurrent thrombosis in patients with polycythemia vera and essential thrombocythemia: incidence, risk factors, and effect of treatments

- Red blood cell transfusion-dependency implies a poor survival in primary myelofibrosis irrespective of International Prognostic Scoring System and Dynamic International Prognostic Scoring System. Full text, Oct 2010.

- Reduced Mortality after Allogeneic Hematopoietic-Cell Transplantation. Full text, Dec 2010.

- Reduced Nausea and Vomiting after Bone Marrow Transplantation with Aprepitant: Oncology Times, Mar 2010.

- Relation between JAK2 (V617F) mutation status, granulocyte activation, and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders. Full text, 2006.

- Relevance of bone marrow features in the differential diagnosis between essential thrombocythemia and early stage idiopathic myelfibrosis. 2000.

- Relevance of JAK2V617F positivity to hematological diseases - survey of samples from a clinical genetics laboratory. Jan 2011.

- Response criteria for essential thrombocythemia and polycythemia vera: result of a European LeukemiaNet consensus conference. May 2009

- Rethinking Disease Definitions and Therapeutic Strategies in Essential Thrombocythemia and Polycythemia Vera. Full text, 2010.

- Risk assessment in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms. March 2011.

- Role of JAK-STAT Signaling in the Pathogenesis of Myeloproliferative Disorders. 2006.

- Role of JAK2 in the Pathogenesis and Therapy of Myeloproliferative Disorders

- Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis. Sep 2010.

- Salient features of hematological diseases. Annals of Oncology. 2007. Full text pdf.

- Selective Inhibition of JAK2-Driven Erythroid Differentiation of Polycythemia Vera Progenitors

- Selective serotonin reuptake inhibitors are effective in the treatment of polycythemia vera-associated pruritus. 2002.

- Serum erythropoietin concentration as a diagnostic tool for polycythemia vera. 2004.

- Sex differences in the JAK2V617F allele burden in the chronic myeloproliferative disorders. Full text, Feb 2010.

- Significant increase in the apparent incidence of essential thrombocythemia related to new WHO diagnostic criteria: a population-based study. April 2009

- Skin Malignancies Associated with Hydroxyurea Use in Myeloproliferative Disorders and Sickle Cell Patients: Incidence and Significance. Full text, 2009.

- Somatic mutations of JAK2 exon 12 in patients with JAK2 (V617F)-negative myeloproliferative disorders. 2008.

- Speak Up: 8 Words & Phrases to Ban in Oncology!! Oncology Times, June 2010.

- Special Issues in Myeloproliferative Neoplasms. Full text, Dec 2010.

- Splanchnic vein thrombosis, the onset manifestation in JAK positive Chronic Myeloproliferative Disorders Neoplasms. April 2011.

- Splenectomy and Risk of Blast Transformation in Myelofibrosis With Myeloid Metaplasia

- Splenectomy and Risk of Blast Transformation in Myelofibrosis With Myeloid Metaplasia. Full text, Nov 2010

- Splenectomy in myelofibrosis with myeloid metaplasia: a single-institution experience with 223 patients. Full text, 2001.

- Splenectomy Normalizes Hematocrit in Murine Polycythemia Vera. Full text, 2009.

- Spontaneous intraabdominal hematomas associated with arterial aneurysms in polycythemia vera. Full text, Nov 2010.

- St Vincent’s 7th Annual Indy Haematology Review: Myeloproliferative Neoplasms, 14 page slide show. March 2010.

- STATistical Power of Clonal Analysis: Differential STAT1 Pathway Activation Downstream of the JAK2V617F Mutation.

- Stem Cell Transplant for Chronic Myeloid Leukemia in the Imatinib Era. Full text, Oct 2010. (free registration needed)

- Stem-Cell Transplant for Polycythemia Vera

- Structural effects of clinically observed mutations in JAK2 exons 13-15: comparison with V617F and exon 12 mutations

- Subclinical hypercortisolism among polycythemia vera patients. Full text, July 2010.

- Successful engraftment after reduced-intensity umbilical cord blood transplantation for myelofibrosis. Full text, April 2010.

- Superior Vena Cava Syndrome in a Patient with Polycythemia Vera: Diagnosis and Treatment

- Survival Data for Patients Younger Than 60 With Primary Myleofibrosis–Mayo Clinic Proceedings. Tefferi video. 2010.

- Survivor Interview Karen T. Myelofibrosis and transplant survivor.

- Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. 2008.

- TET2 gene is not deleted in chronic myelomonocytic leukemia: a FISH retrospective study. Full text, Oct 2010.

- TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia. Full text, Oct 2010.

- Thalidomide and lenalidomide in primary myelofibrosis. Full text, August 2010.

- Thalidomide and lenalidomide in primary myelofibrosis. Full text, Mar 2011.

- Thalidomide therapy in compensated and decompensated myelofibrosis with myeloid metaplasia. 2001.

- Thalidomide versus placebo in myeloid metaplasia with myelofibrosis: a prospective, randomized, double-blind, multicenter study. 2006.

- The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. July 2009

- The ABCCs of myelofibrosis. 2006.

- The allele burden of JAK2 mutations remains stable over several years in patients with myeloproliferative disorders. 2008.

- The American Academy of Dental Sleep Medicine

- The amount of JAK2 617V>F matters

- The Budd?Chiari Syndrome and V617F Mutation in JAK2

- The Burden of Fatigue and Quality of Life in Myeloproliferative Disorders (MPDs) An International Internet-Based Survey of 1179 MPD Patients

- The contribution of...... Commentary: The tale of two coxes.

- The Diagnosis and Management of Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis in the JAK2 V617F Era

- The effect of interferon on the metabolism of LDLs. 1992.

- The Effectiveness of an Online Mind-Body Intervention for Older Adults With Chronic Pain

- The Erythromelalgia Association

- The Forgotten Myeloproliferative Disorder: Myeloid Metaplasia

- The frequency of JAK2 exon 12 mutations in idiopathic erythrocytosis patients with low serum erythropoietin levels. 2007.

- The Genetic Basis of Myeloproliferative Disorders. 2007.

- The hematopoietic stem cell compartment of JAK2V617F-positive myeloproliferative disorders is a reflection of disease heterogeneity. 2008.

- The incidence of the JAK2 V617F mutation in patients with idiopathic erythrocytosis. 2006.

- The Indolent Natural History of Essential Thrombocythemia: A Challenge to New Drug Development. 2005.

- The JAK2 46/1 haplotype confers susceptibility to essential thrombocythemia regardless of JAK2V617F mutational status-clinical correlates in a study of 226 consecutive patients. Abstract, Oct 2009.

- The JAK2 617V>F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera. 2007.

- The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid . 2006.

- The JAK2 V617F somatic mutation, mortality and cancer risk in the general population. Full text, Dec 2010.

- The JAK2V617 mutation induces constitutive activation and agonist hypersensitivity in basophils of polycythemia vera. Sep 2009

- The JAK2V617F Mutation in Polycythemia Vera and Other Myeloproliferative Disorders: One Mutation for Three Diseases?

- The JAK2V617F tyrosine kinase mutation in blood donors with upper-limit haematocrit levels

- The JAK2V617F Tyrosine Kinase Mutation in Myeloproliferative Disorders: Status Report and Immediate Implications for Disease Classification and Diagnosis. 2005.

- The leukemic stem cell niche: current concepts and therapeutic opportunities: AML Aug 2009

- The Long-term Outlook for Essential Thrombocythemia. 2006.

- The Management and Outcome of 18 pregnancies in women with Polycythemia Vera

- The management of cancer pain in the elderly. Full text pdf, 2009.

- The Measurement of Fatigue in Chronic Illness: A Systematic Review of Unidimensional and Multidimensional Fatigue Measures

- The Median Isn't the Message by Stephen Jay Gould

- The Myeloproliferative Disorders Research Consortium

- The natural history and treatment outcome of blast phase BCR-ABL? myeloproliferative neoplasms. 2008.

- The Next Big Rare Disease Drug? (Incyte), Sep 2010.

- The Ph-positive and Ph-negative myeloproliferative neoplasms - some topical preclinical and clinical issues. Full text, Jan 2011.

- The Physician's Guide to Laboratory Test Selection and Interpretation. Myeloproliferative Neoplasms.

- The revised WHO diagnostic criteria for Ph-negative myeloproliferative diseases are not appropriate for the diagnostic screening of childhood polycythemia vera and essential thrombocythemia

- The revised World Health Organization diagnostic criteria for polycythemia vera, essential thrombocytosis and primary myelofibrosis: an alternative proposal: Jerry L. Spivak and Richard T. Silver

- The Role of Point-of-Care Testing in the Early Diagnosis of Pseudo-Hypoxemia in Myeloproliferative Disorders. Full text, June 2010.

- The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms. Full text, Dec 2010.

- The Significance of Bone Marrow Biopsy and JAK2V617F Mutation in the Differential Diagnosis Between the "Early" Prepolycythemic Phase of Polycythemia Vera and Essential Thrombocythemia. 2008.

- The Spleen in Myelofibrosis With Myeloid Metaplasia. 2004.

- The stilbenoid tyrosine kinase inhibitor, G6, suppresses Jak2-V617F mediated human pathological cell growth in vitro and in vivo. Full text, Dec 2010.

- The Thomas Jefferson University Headache Center website

- The V617F mutation of JAK2 is very uncommon in patients with thrombosis. 2007.

- Therapeutic potential of JAK2 inhibitors. Full text, Srdan Verstovsek, 2009.

- Third Age: Primary polycythemia.

- Third-Generation Tyrosine Kinase Inhibitors and Beyond. Full text, Nov 2010.

- Thrombocytosis and Thrombosis

- Thrombocytosis. Full text, 2009.

- Thrombopoietin Receptor Activation, Thrombopoietin Mimetic Drugs, and Hereditary Thrombocytosis: Remarks on Bone Marrow Fibrosis. August 2010.

- Thrombosis in myelofibrosis: prior thrombosis is the only predictive factor and most venous events are provoked. Full text, Oct 2010

- Thrombosis in primary myelofibrosis: incidence and risk factors. Full text, 2010

- Thrombosis Risk Rises in Women With Myeloproliferative Disorders. Full text, Dec 2010.

- TPO-mimetics and myelofibrosis? A reticulin question!

- Transcription factor mutations in myelodysplastic/myeloproliferative neoplasms. Full text, April 2010.

- Transformation of Polycythemia Vera to Chronic Myelogenous Leukemia. 2007.

- Treating depression in older cancer patients

- Treatment of Chronic Pruritus with the Selective Serotonin Re-uptake Inhibitors Paroxetine and Fluvoxamine: Results of an Open-labelled, Two-arm Proof-of-concept Study.

- Treatment of myeloproliferative neoplasms except for chronic leukemia

- Treatment of Polycythemia Vera: A Clinical Oncology Perspective

- Treatment of Polycythemia Vera: The Use of Hydroxyurea and Pipobroman in 292 Patients Under the Age of 65 Years

- Treatment Options for Essential Thrombocythemia and Polycythemia Vera

- Twenty-five years of epidemiological recording on myeloid malignancies: data from the specialized registry of hematological malignancies of Côte d’Or (Burgundy, France). Full text, Oct 2010.

- Type 1 Diabetes Caused by Interferon α-2α in Polycythemia Vera Therapy. Full text, Nov 2010.

- Types of Stem Cell Transplantation

- Tyrosine Kinase Mutations in Myeloproliferative Neoplasms. Full text, 2010.

- Understanding and Evaluating Platelet Function. Full text, 2010.

- Understanding Interferon: Centre for Immune Research.

- Understanding Of Blood Cell Development Challenged By Discovery That Platelets Can Reproduce In Circulation. Jan 2010.

- Understanding the interplay between JAK2 and SOCS3 in myeloproliferative disease. Research project 2010, Walter and Eliza Hall Institute of Medical Research.

- University of Toronto, Canada, Division of Hematology: Treatment policies. Essential Thrombocythemia.

- University of Toronto, Canada, Division of Hematology: Treatment policies. Myelofibrosis.

- University of Toronto, Canada, Division of Hematology: Treatment policies. Polycythemia Vera.

- Untangling the Web — Patients, Doctors, and the Internet. March 2010.

- V617F "JAKs" up myeloproliferative signal. 2005.

- V617F mutation in JAK2 is associated with poorer survival in idiopathic myelofibrosis. 2006.

- Value of bone marrow biopsy in the diagnosis of essential thrombocythemia. 2004.

- Vascular and Neoplastic Risk in a Large Cohort of Patients with Polycythemia Vera

- Vascular complications after splenectomy for hematologic disorders

- Vascular Medicine: JAK2. April 2010.

- Vitamin D for Cancer Prevention: Global Perspective

- What can be found in a Peripheral Blood Film: A very useful PatientPlus Article.

- What is a gene mutation and how do mutations occur?

- When and How to Treat Essential Thrombocythemia. Full text, 2005.

- WHO 2008 Classification of Myeloid Neoplasms – What is new and why?

- WP1066, a Novel JAK2 Inhibitor, Suppresses Proliferation and Induces Apoptosis in Erythroid Human Cells Carrying the JAK2 V617F Mutation. 2008.

- ZFP36L1 Negatively Regulates Erythroid Differentiation of CD34+ Hematopoietic Stem Cells by Interfering with Stat5b Pathway. Full text, August 2010.